Does eloralintide make you tired?

Fatigue was one of the two most common adverse events in the phase 2 trial, along with nausea. Rates rose with dose: 0% at 1 mg, 13% at 3 mg, 29% at 6 mg and 43% at 9 mg, compared with 12% on placebo. The 6 to 9 mg escalation arm reported 46%, so starting dose and escalation pace both seem to matter.

Why amylin agonists cause fatigue isn’t settled. Reduced food intake is one likely factor, and the phase 2 groups were small, so those rates are rough. Researchers studying it in animals can track activity, food intake and body weight together over time. Our eloralintide explainer has the full adverse event table. Shop eloralintide for laboratory research.