Is Ipamorelin better than Sermorelin?

Neither is better overall, because they act on different receptors. Ipamorelin binds the ghrelin receptor, while sermorelin, the first 29 amino acids of GHRH, binds the GHRH receptor on the same pituitary cells. Sermorelin was once FDA approved as Geref for growth hormone deficiency in children until its maker discontinued it in 2008. Ipamorelin never reached approval for any use.

Because the two receptors work together, activating both produces a larger growth hormone pulse than either alone. That’s why many study designs compare ipamorelin with and without a GHRH analog such as Sermorelin 10mg in the same model, or CJC No DAC. Neither is approved for human use as sold here. Buy Ipamorelin Peptide online for growth hormone research.